DAZL anticorps (C-Term)

N° du produit ABIN2778769

L’anticorps anti-DAZL Polyclonal Lapin est utilisé pour la détection de DAZL dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval et Mouton. Il a été validé pour WB.

Aperçu rapide pour DAZL anticorps (C-Term) (ABIN2778769)

Antigène: DAZL (Deleted in Azoospermia-Like (DAZL))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAZL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DAZL anticorps

Épitope: C-Term

Fonction: DAZL Antibody - C-terminal region

Séquence: EVDPGAEVVP NECSVHEATP PSGNGPQKKS VDRSIQTVVS CLFNPENRLR

Homologie: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 93%, Rat: 86%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DAZL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DAZL

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40356-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DAZL

Antigène: DAZL (Deleted in Azoospermia-Like (DAZL))

Autre désignation: DAZL

Sujet:

Background Information: DAZ (Deleted in AZoospermia) is the potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. DAZL is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of the autosomal gene encoding DAZL during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in the Dazl gene have been linked to severe spermatogenic failure and infertility in males.The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Deleted in azoospermia-like

Alternative Symbols: DAZH, DAZL1, DAZLA, SPGYLA

Protein Name: Deleted in azoospermia-like

Poids moléculaire: 33kDa

ID gène: 1618

NCBI Accession: NP_001342

UniProt: Q92904