EIF4G2 anticorps (N-Term)

N° du produit ABIN2778774

Détail du produit anti-EIF4G2 anticorps

Antigène: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF4G2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PNFDGPAAEG QPGQKQSTTF RRLLISKLQD EFENRTRNVD VYDKRENPLL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EIF4G2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4G2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 907 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EIF4G2

Antigène: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Autre désignation: EIF4G2 (EIF4G2 Produits)

Synonymes: anticorps AAG1, anticorps DAP5, anticorps NAT1, anticorps P97, anticorps NAT1B, anticorps eif4g2, anticorps hm:zeh1307, anticorps wu:fa14h01, anticorps wu:fb44h01, anticorps wu:fb59c06, anticorps wu:fc21b05, anticorps EIF4G2, anticorps AA589388, anticorps DAP-5, anticorps E130105L11Rik, anticorps Nat1, anticorps Natm1, anticorps p97, anticorps NAT1A, anticorps im:7148615, anticorps wu:fb81f07, anticorps wu:fb82b06, anticorps wu:fb98h08, anticorps dap5, anticorps eif4g2.L, anticorps nat1, anticorps eukaryotic translation initiation factor 4 gamma 2, anticorps eukaryotic translation initiation factor 4, gamma 2b, anticorps eukaryotic translation initiation factor 4, gamma 2, anticorps eukaryotic translation initiation factor 4 gamma, 2, anticorps eIF4G-related protein NAT1, anticorps eukaryotic translation initiation factor 4, gamma 2a, anticorps eukaryotic translation initiation factor 4 gamma, 2 S homeolog, anticorps EIF4G2, anticorps eif4g2b, anticorps Eif4g2, anticorps nat1, anticorps eif4g2a, anticorps eif4g2.S

Sujet: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. EIF4G2 shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, EIF4G2 functions as a general repressor of translation by forming translationally inactive complexes. Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Alias Symbols: AAG1, DAP5, FLJ41344, NAT1, p97, P97
Protein Interaction Partner: SUMO2, UBC, SKIL, RPA2, ITGA4, FN1, Dlg4, POLDIP3, SLIRP, EIF4G3, RAB7A, EIF4H, EIF4G1, EIF4B, EIF4A1, DCUN1D1, EIF3F, MKNK1, EIF2S2, EIF3A, EIF5, EIF4A2, CASP3, NCBP1, EIF4E, MAGEA6,
Protein Size: 907

Poids moléculaire: 102 kDa

ID gène: 1982

NCBI Accession: NM_001418, NP_001409

UniProt: P78344