HNRNPK anticorps (C-Term)

N° du produit ABIN2778791

Cet anticorps anti-HNRNPK est un anticorps Lapin Polyclonal détectant HNRNPK dans WB et IHC. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Poisson zèbre (Danio rerio), Cobaye, Chévre et Cheval.

Aperçu rapide pour HNRNPK anticorps (C-Term) (ABIN2778791)

Antigène: HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Poisson zèbre (Danio rerio), Cobaye, Chévre, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HNRNPK anticorps

Épitope: C-Term

Séquence: YSYAGGRGSY GDLGGPIITT QVTIPKDLAG SIIGKGGQRI KQIRHESGAS

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HNRPK. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HNRPK

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 463 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HNRNPK

Antigène: HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

Autre désignation: HNRPK

Sujet: HNRPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Multiple alternatively spliced transcript variants have been described for this gene but only three variants have been fully described.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Multiple alternatively spliced transcript variants have been described for this gene but only three variants have been fully described.
Alias Symbols: CSBP, TUNP, HNRPK
Protein Interaction Partner: ZNF385C, ZFC3H1, RBMY1F, ZNF792, HNRNPLL, YTHDC1, PRR3, CCDC33, FBXL18, MARK4, PCDHB14, DALRD3, RASD1, RBMX, PRPF31, SORBS3, ABI2, HUWE1, MATR3, QKI, UBC, U2AF1, TYK2, TP53, SPG7, ZNRF2P1, C6orf226, RTP5, AQP5, GRB2, FUS, DOCK2, CIRBP, SNRPA, RBMY1A1, RBM
Protein Size: 463

Poids moléculaire: 51 kDa

ID gène: 3190

NCBI Accession: NM_031262, NP_112552

UniProt: P61978