ISG20 anticorps (N-Term)

N° du produit ABIN2778795

Cité dans 2 publications. Cet anticorps anti-ISG20 Polyclonal Lapin (ABIN2778795) détecte spécifiquement ISG20 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Chien, Cheval, Boeuf (Vache), Porc, Cobaye et Lapin.

Aperçu rapide pour ISG20 anticorps (N-Term) (ABIN2778795)

Antigène: ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))

Reactivité: Humain, Rat, Souris, Chien, Cheval, Boeuf (Vache), Porc, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISG20 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ISG20 anticorps

Épitope: N-Term

Fonction: ISG20 Antibody - N-terminal region

Séquence: GAVLYDKFIR PEGEITDYRT RVSGVTPQHM VGATPFAVAR LEILQLLKGK

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ISG20. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ISG20

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40392-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ISG20 (ABIN2778795)

Zahoor, Xue, Sato, Murakami, Takeshima, Aida: "HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages." dans: PLoS ONE, Vol. 9, Issue 8, pp. e106418, (2014) (PubMed).

Horio, Murai, Inoue, Hamasaki, Tanaka, Ohgi: "Crystal structure of human ISG20, an interferon-induced antiviral ribonuclease." dans: FEBS letters, Vol. 577, Issue 1-2, pp. 111-6, (2004) (PubMed).

Détails sur ISG20

Antigène: ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))

Autre désignation: ISG20

Sujet:

Background Information: ISG20 belongs to the the exonuclease superfamily. It is exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. It degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. It is involved in the antiviral function of IFN against RNA viruses.

Gene Name: Interferon stimulated exonuclease gene 20 kDa

Alternative Symbols: CD25, HEM45

Protein Name: Interferon-stimulated gene 20 kDa protein

Poids moléculaire: 20kDa

ID gène: 3669

NCBI Accession: NP_002192

UniProt: Q96AZ6