PPP1R8 anticorps (Middle Region)

N° du produit ABIN2778806

Cet anticorps anti-PPP1R8 Polyclonal Lapin (ABIN2778806) détecte spécifiquement PPP1R8 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour PPP1R8 anticorps (Middle Region) (ABIN2778806)

Antigène: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1R8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PPP1R8 anticorps

Épitope: Middle Region

Fonction: PPP1R8 Antibody - middle region

Séquence: PNLAPDVDLT PVVPSAVNMN PAPNPAVYNP EAVNEPKKKK YAKEAWPGKK

Specificité: This antibody recognizes isoform-gamma

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Attributs du produit: This is a rabbit polyclonal antibody against PPP1R8. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PPP1R8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40412-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PPP1R8

Antigène: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Autre désignation: PPP1R8

Sujet:

Background Information: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

Gene Name: Protein phosphatase 1, regulatory subunit 8

Alternative Symbols: ARD1, ARD-1, NIPP1, NIPP-1, PRO2047

Protein Name: Nuclear inhibitor of protein phosphatase 1

Poids moléculaire: 14kDa

ID gène: 5511

NCBI Accession: NP_002704

UniProt: Q12972