SRGN anticorps (Middle Region)

N° du produit ABIN2778809

Détail du produit anti-SRGN anticorps

Antigène: SRGN (serglycin (SRGN))

Épitope: Middle Region

Reactivité: Humain, Lapin, Rat, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRGN est non-conjugé

Application: Western Blotting (WB)

Séquence: RTDLFPKTRI QDLNRIFPLS EDYSGSGFGS GSGSGSGSGS GFLTEMEQDY

Homologie: Guinea Pig: 78%, Horse: 100%, Human: 100%, Pig: 91%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SRGN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SRGN

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 158 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SRGN

Antigène: SRGN (serglycin (SRGN))

Autre désignation: SRGN (SRGN Produits)

Synonymes: anticorps PPG, anticorps PRG, anticorps PRG1, anticorps Prg, anticorps Prg1, anticorps Sgc, anticorps Pgsg, anticorps serglycin, anticorps SRGN, anticorps Srgn

Sujet: SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. SRGN was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ12930, MGC9289, PPG, PRG, PRG1
Protein Interaction Partner: UBQLN1, SGTA, UBQLN4, PSRC1, CEP70, UBR4, BAG6, CCL3, PF4, GZMB, CD44, ALB,
Protein Size: 158

Poids moléculaire: 18 kDa

ID gène: 5552

NCBI Accession: NM_002727, NP_002718

UniProt: P10124

Pathways: Maintenance of Protein Location