PSMA6 anticorps (N-Term)

N° du produit ABIN2778812

Cet anticorps Lapin Polyclonal détecte spécifiquement PSMA6 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Chévre, Cobaye, Cheval, Mouton, Poisson zèbre (Danio rerio) et Saccharomyces cerevisiae.

Aperçu rapide pour PSMA6 anticorps (N-Term) (ABIN2778812)

Antigène: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Chévre, Cobaye, Cheval, Mouton, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMA6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PSMA6 anticorps

Épitope: N-Term

Séquence: EYAFKAINQG GLTSVAVRGK DCAVIVTQKK VPDKLLDSST VTHLFKITEN

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PSMA6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PSMA6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 246 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PSMA6

Antigène: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Autre désignation: PSMA6

Sujet: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA6 is a member of the peptidase T1A family, which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IOTA, MGC22756, MGC2333, MGC23846, PROS27, p27K
Protein Interaction Partner: UBC, RNF170, LIMD2, C19orf57, TRIM39, ZBTB44, CADM1, HUWE1, PSMA3, RTP5, KRTAP4-2, AURKA, PSMD14, MDM2, PSMA5, PSMG3, PSMG2, PSMG1, RNF2, PSMB8, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3, PSMB2, PSMB1, PSMA7, PSMA4, PSMA1, HNRNPA2B1, PYCRL, RPP38, RPP30, CAST, PS
Protein Size: 246

Poids moléculaire: 27 kDa

ID gène: 5687

NCBI Accession: NM_002791, NP_002782

UniProt: P60900

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA