SNRPB anticorps (Middle Region)
Aperçu rapide pour SNRPB anticorps (Middle Region) (ABIN2778832)
Antigène
Voir toutes SNRPB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- LRGENLVSMT VEGPPPKDTG IARVPLAGAA GGPGIGRAAG RGIPAGVPMP
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against SNRPB. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SNRPB
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 231 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))
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Autre désignation
- SNRPB
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Sujet
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SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
Alias Symbols: COD, SNRPB1, SmB/SmB', snRNP-B, SmB/B', Sm-B/B'
Protein Interaction Partner: RFX6, KRT40, L3MBTL3, GOLGA2, DAB1, TRIM23, CEP55, BANP, SS18L1, TFIP11, RBPMS, CD2BP2, CALCOCO2, HUWE1, PNMA1, PSMA3, UBC, LIN28A, MEPCE, RPA3, RPA2, RPA1, SF3A3, NCS1, CDKN2A, SRPK3, PRPF4B, SRPK2, SKIV2L, ICAM1, CD81, IGSF8, PAN2, Snrpc, LSM8, SNRPD3,
Protein Size: 231 -
Poids moléculaire
- 24 kDa
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ID gène
- 6628
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NCBI Accession
- NM_003091, NP_003082
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UniProt
- Q66K91
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Antigène
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