XPO1 anticorps (Middle Region)

N° du produit ABIN2778850

L’anticorps anti-XPO1 Polyclonal Lapin est utilisé pour la détection de XPO1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio), Lapin, Porc et Cobaye. Il a été validé pour WB et IHC.

Aperçu rapide pour XPO1 anticorps (Middle Region) (ABIN2778850)

Antigène: XPO1 (Exportin 1 (XPO1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio), Lapin, Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XPO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-XPO1 anticorps

Épitope: Middle Region

Fonction: XPO1 Antibody - middle region

Séquence: IPAFKEHLRD FLVQIKEFAG EDTSDLFLEE REIALRQADE EKHKRQMSVP

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against XPO1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human XPO1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40466-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur XPO1

Antigène: XPO1 (Exportin 1 (XPO1))

Autre désignation: XPO1

Sujet:

Background Information: XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is also involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Exportin 1 (CRM1 homolog, yeast)

Alternative Symbols: emb, CRM1, exp1, CRM-1

Protein Name: Exportin-1

Poids moléculaire: 123kDa

ID gène: 7514

NCBI Accession: NP_003391

UniProt: O14980

Pathways: M Phase