YARS anticorps (N-Term)

N° du produit ABIN2778856

Détail du produit anti-YARS anticorps

Antigène: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YARS est non-conjugé

Application: Western Blotting (WB)

Séquence: MGDAPSPEEK LHLITRNLQE VLGEEKLKEI LKERELKIYW GTATTGKPHV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against YARS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human YARS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 528 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur YARS

Antigène: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Autre désignation: YARS (Yars Produits)

Synonymes: anticorps CMTDIC, anticorps TYRRS, anticorps YRS, anticorps YTS, anticorps AL024047, anticorps AU018965, anticorps cb204, anticorps wu:fk52b08, anticorps YARS, anticorps cmtdic, anticorps tyrrs, anticorps yrs, anticorps yts, anticorps CG4561, anticorps Dmel\\CG4561, anticorps TyrRS, anticorps anon-EST:Posey261, anticorps dYARS, anticorps GB10789, anticorps tyrosyl-tRNA synthetase, anticorps tyrosyl-tRNA synthetase L homeolog, anticorps tyrosyl-tRNA synthetase, putative, anticorps tyrosine--tRNA ligase, anticorps Tyrosyl-tRNA synthetase, anticorps tyrosine--tRNA ligase, cytoplasmic, anticorps YARS, anticorps Yars, anticorps yars, anticorps yars.L, anticorps MAL8P1.125, anticorps MEFER_RS04475, anticorps TyrRS, anticorps LOC413909, anticorps LOC100163888, anticorps LOC100282315

Sujet: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. Sequence Note: The RefSeq transhttp://www.ncbi.nlm.nih.gov/projects/locusXref/oho.cgi?server= REFTRACK&frm=0x66adf650&appid=0&evId=1&evIntpar=8565&evStrpar=&frmA n=EditApp LocusXref: edit YARS(8565)cript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMTDIC, TYRRS, YRS, YTS
Protein Interaction Partner: UBC, SARNP, NRD1, HSPA8, VCAM1, ITGA4, FN1, METTL16, XRCC5, DYNC1H1, CDK2, ELANE, EIF1B, SAP18, EIF6, ARF6,
Protein Size: 528

Poids moléculaire: 59 kDa

ID gène: 8565

NCBI Accession: NM_003680, NP_003671

UniProt: P54577