RBM8A anticorps (N-Term)

N° du produit ABIN2778928

Détail du produit anti-RBM8A anticorps

Antigène: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM8A est non-conjugé

Application: Western Blotting (WB)

Séquence: EDFAMDEDGD ESIHKLKEKA KKRKGRGFGS EEGSRARMRE DYDSVEQDGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Rbm8a. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Rbm8a

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 174 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RBM8A

Antigène: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Autre désignation: Rbm8a (RBM8A Produits)

Synonymes: anticorps BOV-1A, anticorps BOV-1B, anticorps BOV-1C, anticorps C1DELq21.1, anticorps DEL1q21.1, anticorps MDS014, anticorps RBM8, anticorps RBM8B, anticorps TAR, anticorps Y14, anticorps ZNRP, anticorps ZRNP1, anticorps 2310057C03Rik, anticorps AA673428, anticorps Rbm8, anticorps RBM8A, anticorps rbm8, anticorps rbm8a, anticorps rnp-5, anticorps fb34f03, anticorps wu:fb34f03, anticorps zgc:110525, anticorps rbm8-A, anticorps rbm8a-A, anticorps rbm8-B, anticorps RNA binding motif protein 8A, anticorps RNA binding motif protein 8a, anticorps RNA binding motif protein 8A S homeolog, anticorps RNA binding motif protein 8A L homeolog, anticorps RBM8A, anticorps Rbm8a, anticorps rbm8a, anticorps rbm8a.S, anticorps rbm8a.L

Sujet: Rbm8a is a component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mRNA and thereby influences downstream processes of gene expression including mRNA splicing, nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). The heterodimer MAGOH-RBM8A interacts with PYM that function to enhance the translation of EJC-bearing spliced mRNAs by recruiting them to the ribosomal 48S preinitiation complex.
Alias Symbols: Rbm8
Protein Interaction Partner: Stau2,
Protein Size: 174

Poids moléculaire: 19 kDa

ID gène: 295284

NCBI Accession: XM_215637, XP_215637

UniProt: Q27W01