RBM8A anticorps (N-Term)
Aperçu rapide pour RBM8A anticorps (N-Term) (ABIN2778929)
Antigène
Voir toutes RBM8A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- LHEAGGEDFA MDEDGDESIH KLKEKAKKRK GRGFGSEEGS RARMREDYDS
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Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 82%, Rabbit: 82%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against RBM8A. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human RBM8A
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 174 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RBM8A (RNA Binding Motif Protein 8A (RBM8A))
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Autre désignation
- RBM8A
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Sujet
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RBM8A is a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events.This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B, it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.
Alias Symbols: Y14, RBM8, ZNRP, RBM8B, ZRNP1, BOV-1A, BOV-1B, BOV-1C, MDS014
Protein Interaction Partner: MAGOHB, MAGOH, UBC, SUZ12, RNF2, PARK2, SRPK2, SRPK1, FBXO25, tat, UPF3B, SMG9, SMG8, PABPC1, UPF2, SMG5, SMG1, RUVBL2, RBM8A, SMG7, EIF4A3, TTI1, RUVBL1, UPF1, NCBP2, TOE1, SF3B2, RPS16, RPL11, HBB, GSPT1, ZFP36L1, UNC119B, SLIRP, LSM2, CIAPIN1, TFCP2L1,
Protein Size: 174 -
Poids moléculaire
- 19 kDa
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ID gène
- 9939
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NCBI Accession
- NM_005105, NP_005096
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UniProt
- Q9Y5S9
Antigène
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