Snurportin 1 anticorps (Middle Region)

N° du produit ABIN2778945

Cet anticorps anti-Snurportin 1 est un anticorps Lapin Polyclonal détectant Snurportin 1 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Cheval et Porc.

Aperçu rapide pour Snurportin 1 anticorps (Middle Region) (ABIN2778945)

Antigène: Snurportin 1 (SNUPN)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Snurportin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Snurportin 1 anticorps

Épitope: Middle Region

Séquence: GVAVPAGPLT TKPDYAGHQL QQIMEHKKSQ KEGMKEKLTH KASENGHYEL

Homologie: Cow: 85%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SNUPN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SNUPN

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 360 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Snurportin 1

Antigène: Snurportin 1 (SNUPN)

Autre désignation: SNUPN

Sujet: The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: KPNBL, RNUT1, Snurportin1
Protein Interaction Partner: UBC, HOTAIR, MEX3B, XPO1, GCNT3, RNF126, DBN1, RPL17, KPNB1, PAFAH1B2, TNNT3, PEX5, ENO2, RAN, DDX20, ZPR1, SNRPB, SMN1,
Protein Size: 360

Poids moléculaire: 41 kDa

ID gène: 10073

NCBI Accession: NM_005701, NP_005692

UniProt: O95149

Pathways: Ribonucleoprotein Complex Subunit Organization, Protein targeting to Nucleus