HNRNPR anticorps (N-Term)

N° du produit ABIN2778950

Cet anticorps Lapin Polyclonal détecte spécifiquement HNRNPR dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin et Boeuf (Vache) et a été mentionné dans 1 publication.

Aperçu rapide pour HNRNPR anticorps (N-Term) (ABIN2778950)

Antigène: HNRNPR (Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HNRNPR anticorps

Épitope: N-Term

Séquence: ANQVNGNAVQ LKEEEEPMDT SSVTHTEHYK TLIEAGLPQK VAERLDEIFQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HNRNPR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRNPR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 633 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HNRNPR (ABIN2778950)

Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." dans: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).

Détails sur HNRNPR

Antigène: HNRNPR (Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR))

Autre désignation: HNRNPR

Sujet: HNRNPR belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene.
Alias Symbols: FLJ25714, HNRPR, hnRNP-R, hnRNP R
Protein Interaction Partner: PRMT1, KHDRBS2, CEP250, SUMO2, IVNS1ABP, STAU1, UBC, MDM2, WWOX, ZBTB1, RPA3, RPA2, RPA1, RNF2, EED, rev, PPP4R1, MTA2, CCDC6, EHBP1L1, RABEP2, BRCC3, SMEK1, LSM8, LARP7, GAPVD1, CD2AP, WDHD1, SF3A1, TRIM28, HDAC1, NR3C1, POLR2C, POLR2A, MAP4, PARK2, SRPK
Protein Size: 633

Poids moléculaire: 71 kDa

ID gène: 10236

NCBI Accession: NM_005826, NP_005817

UniProt: O43390