SFRS6 anticorps (Middle Region)

N° du produit ABIN2778972

Détail du produit anti-SFRS6 anticorps

Antigène: SFRS6 (SRSF6) (serine/arginine-Rich Splicing Factor 6 (SRSF6))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Lapin, Poisson zèbre (Danio rerio), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SFRS6 est non-conjugé

Application: Western Blotting (WB)

Séquence: KERTNEGVIE FRSYSDMKRA LDKLDGTEIN GRNIRLIEDK PRTSHRRSYS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against SFRS6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SFRS6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 344 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SFRS6 (ABIN2778972)

Gautrey, Tyson-Capper: "Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells." dans: PLoS ONE, Vol. 7, Issue 12, pp. e51497, (2013) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur SFRS6

Antigène: SFRS6 (SRSF6) (serine/arginine-Rich Splicing Factor 6 (SRSF6))

Autre désignation: SFRS6 (SRSF6 Produits)

Sujet: SFRS6 is involved in mRNA splicing and may play a role in the determination of alternative splicing. It belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12.The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: B52, MGC5045, SRP55, SFRS6
Protein Interaction Partner: LUC7L2, TP53, MDM2, ASB18, SUZ12, EED, RPL24, SRPK2, SRPK1, SRPK3, TARDBP, YWHAE, PAN2, TOE1, SF3B4, RBM10, UBC, TRA2B, EIF4A3, MAGOH, ESR1, BARD1, SRSF10, APP, CAND1, COPS5, SRRM1, CUL1, CUL2, TERF2, TERF1, HNRNPA1, SF3A2, ELAVL1, SREK1, AI837181, CLK1,
Protein Size: 344

Poids moléculaire: 39 kDa

ID gène: 6431

NCBI Accession: NM_006275, NP_006266

UniProt: Q13247

Pathways: Ribonucleoprotein Complex Subunit Organization