PRPF8 anticorps (N-Term)

N° du produit ABIN2778986

L’anticorps Lapin Polyclonal anti-PRPF8 a été validé pour WB. Il convient pour détecter PRPF8 dans des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour PRPF8 anticorps (N-Term) (ABIN2778986)

Antigène: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRPF8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRPF8 anticorps

Épitope: N-Term

Séquence: SHRHSVKSQE PLPDDDEEFE LPEFVEPFLK DTPLYTDNTA NGIALLWAPR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PRPF8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PRPF8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 2335 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRPF8

Antigène: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Autre désignation: PRPF8

Sujet: Pre-mRNA splicing occurs in 2 sequential transesterification steps. PRPF8 is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. The gene encoding PRPF8 is a candidate gene for autosomal dominant retinitis pigmentosa.Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HPRP8, PRP8, PRPC8, RP13
Protein Interaction Partner: SNRNP200, PRPF8, EFTUD2, UBC, CDKN1A, SUMO2, SUMO3, STAU1, LGR4, NEDD8, ERG, ASB15, WWOX, RPA3, RPA2, RPA1, EED, RNF2, SUZ12, rev, PIN1, NEDD4, FBXO6, PRPF4B, UBD, IGSF8, ICAM1, SND1, SF3B2, SLU7, ZNF830, WDR83, PRPF19, GPKOW, FN1, BCAS2, SF3B4, RBM5, VCA
Protein Size: 2335

Poids moléculaire: 273 kDa

ID gène: 10594

NCBI Accession: NM_006445, NP_006436

UniProt: Q6P2Q9