DIS3 anticorps (N-Term)

N° du produit ABIN2779073

Cet anticorps anti-DIS3 est un anticorps Lapin Polyclonal détectant DIS3 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval, Cobaye et Porc.

Aperçu rapide pour DIS3 anticorps (N-Term) (ABIN2779073)

Antigène: DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DIS3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DIS3 anticorps

Épitope: N-Term

Séquence: DIVAVELLPK SQWVAPSSVV LHDEGQNEED VEKEEETERM LKTAVSEKML

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DIS3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DIS3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 958 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DIS3

Antigène: DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))

Autre désignation: DIS3

Sujet: DIS3, belonging to the ribonuclease II (RNB) family, has a 3'-5' exonuclease activity. It is a catalytic component of the exosome 3'->5' exoribonuclease complex required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and for mRNA decay. The protein is implicated in mitotic control and essential for cell division and spore germination. It may be involved in regulating protein dephosphorylation during mitosis.
Alias Symbols: DKFZp667L1817, FLJ10484, KIAA1008, MGC33035, RP11-342J4.3, RRP44, bA555G22.1, dis3p, EXOSC11
Protein Interaction Partner: SUMO2, UBC, TWF1, NTMT1, EXOSC8, EXOSC10, AICDA, WDR1, STXBP3, PPP5C, SH3PXD2B, EXOSC5, EXOSC4, EXOSC1, EXOSC3, SKIV2L2, EXOSC2, EXOSC7, DIS3, EXOSC9, CUL3, CUL5, SIRT7, BABAM1, EXOSC6, MPP6, ZBTB17,
Protein Size: 958

Poids moléculaire: 109 kDa

ID gène: 22894

NCBI Accession: NM_014953, NP_055768

UniProt: Q9Y2L1