OAS2 anticorps (N-Term)

N° du produit ABIN2779106

L’anticorps Lapin Polyclonal anti-OAS2 a été validé pour WB. Il convient pour détecter OAS2 dans des échantillons de Humain, Porc, Lapin, Chien, Boeuf (Vache), Rat et Cheval.

Aperçu rapide pour OAS2 anticorps (N-Term) (ABIN2779106)

Antigène: OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))

Reactivité: Humain, Porc, Lapin, Chien, Boeuf (Vache), Rat, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OAS2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-OAS2 anticorps

Épitope: N-Term

Séquence: DEMVNTICDV LQEPEQFPLV QGVAIGGSYG RKTVLRGNSD GTLVLFFSDL

Homologie: Cow: 92%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against OAS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human OAS2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 687 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur OAS2

Antigène: OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))

Autre désignation: OAS2

Sujet: OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: MGC78578
Protein Interaction Partner: UBC, CLK3, APP,
Protein Size: 687

Poids moléculaire: 79 kDa

ID gène: 4939

NCBI Accession: NM_002535, NP_002526

Pathways: Hepatitis C