CPSF2 anticorps (N-Term)

N° du produit ABIN2779108

Cet anticorps Lapin Polyclonal détecte spécifiquement CPSF2 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin et Poisson zèbre (Danio rerio).Il a été cité dans 1 publication.

Aperçu rapide pour CPSF2 anticorps (N-Term) (ABIN2779108)

Antigène: CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPSF2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CPSF2 anticorps

Épitope: N-Term

Séquence: YAVGKLGLNC AIYATIPVYK MGQMFMYDLY QSRHNTEDFT LFTLDDVDAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CPSF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CPSF2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 782 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CPSF2 (ABIN2779108)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur CPSF2

Antigène: CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

Autre désignation: CPSF2

Sujet: CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.
Alias Symbols: CPSF100, KIAA1367
Protein Interaction Partner: RBBP6, UBC, WWOX, EZH2, rev, HECW2, CLK2, NPM1, CPSF3, SYMPK, CSTF2, MDC1, ECT2, BARD1, GTF3C6, FIP1L1, WDR33, POLE3, CPSF1, RALBP1, MED17, GTF3C3, SMARCD3, SMARCA4, POLR2A, CUL3, HNRNPA1, ELAVL1, SUMO2, SMARCAD1, CSTF2T, RRAGA, TBP, PSMA3, CLP1, CDC73, R
Protein Size: 782

Poids moléculaire: 88 kDa

ID gène: 53981

NCBI Accession: NM_017437, NP_059133

UniProt: Q9P2I0