RNP anticorps (Middle Region)

N° du produit ABIN2779114

L’anticorps Lapin Polyclonal anti-RNP a été validé pour WB. Il convient pour détecter RNP dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin et Saccharomyces cerevisiae.

Aperçu rapide pour RNP anticorps (Middle Region) (ABIN2779114)

Antigène: RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RNP anticorps

Épitope: Middle Region

Séquence: LHAPLPPTSP QPPEEPPLPD EDEELSSEES EYESTDDEDR QRMNKLMELA

Homologie: Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 92%, Rat: 85%, Yeast: 77%

Attributs du produit: This is a rabbit polyclonal antibody against RNPC3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RNPC3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 517 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNP

Antigène: RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))

Autre désignation: RNPC3

Sujet: RNPC3 is an RNA-binding protein involved in pre-mRNA splicing. RNPC3 participates in pre-mRNA U12-dependent splicing. RNPC3 binds to the 3'-stem-loop of m7G-capped U12 snRNA.Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99 % of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
Alias Symbols: FLJ20008, FLJ25070, KIAA183, RBM40, RNP
Protein Interaction Partner: SMAD2, CPSF1, CDK19, RPS3A, APP, PRNP, RNU11, RNU12-2P,
Protein Size: 517

Poids moléculaire: 58 kDa

ID gène: 55599

NCBI Accession: NM_017619, NP_060089

UniProt: Q96LT9