NXF3 anticorps (C-Term)

N° du produit ABIN2779117

Cet anticorps anti-NXF3 est un anticorps Lapin Polyclonal détectant NXF3 dans WB et IHC. Adapté pour Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin et Rat.

Aperçu rapide pour NXF3 anticorps (C-Term) (ABIN2779117)

Antigène: NXF3 (Nuclear RNA Export Factor 3 (NXF3))

Reactivité: Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NXF3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-NXF3 anticorps

Épitope: C-Term

Séquence: SSFLVDMWYQ TEWMLCFSVN GVFKEVEGQS QGSVLAFTRT FIATPGSSSS

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 77%, Horse: 79%, Human: 100%, Pig: 92%, Rabbit: 92%, Rat: 77%

Attributs du produit: This is a rabbit polyclonal antibody against NXF3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human NXF3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 531 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NXF3

Antigène: NXF3 (Nuclear RNA Export Factor 3 (NXF3))

Autre désignation: NXF3

Sujet: NXF3 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF3 has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
Protein Interaction Partner: NXT2, NXT1, SKIL, NXF1, HHV8GK18_gp81, HNRNPUL1, XPO1, NUP214,
Protein Size: 531

Poids moléculaire: 58 kDa

ID gène: 56000

NCBI Accession: NM_022052, NP_071335

UniProt: Q9H4D5