ZNF496 anticorps (Middle Region)

N° du produit ABIN486781

Cet anticorps Lapin Polyclonal détecte spécifiquement ZNF496 dans WB. Il présente une réactivité avec des échantillons de Souris, Humain, Rat, Boeuf (Vache), Mouton, Chien, Cheval, Porc et Lapin.

Aperçu rapide pour ZNF496 anticorps (Middle Region) (ABIN486781)

Antigène: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Reactivité: Souris, Humain, Rat, Boeuf (Vache), Mouton, Chien, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF496 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ZNF496 anticorps

Épitope: Middle Region

Séquence: QEKPHECSVC GELFSDSEDL DGHLESHEAQ KPYRCGACGK SFRLNSHLLS

Homologie: Cow: 86%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ZNF496. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ZNF496

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 587 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ZNF496

Antigène: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Autre désignation: ZNF496

Sujet: ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
Alias Symbols: MGC15548, NIZP1, ZKSCAN17, ZFP496
Protein Interaction Partner: ZKSCAN4, ZSCAN22, ZNF483, ZNF446, ZSCAN12, ZSCAN21, ARR3, Nsd1, SUMO2, UBC, CBX3, TRIM28, NR3C1, POLR3D, ZZZ3, JADE2, RAI1, SSX3, SUPT5H, PPARG,
Protein Size: 587

Poids moléculaire: 67 kDa

ID gène: 84838

NCBI Accession: NM_032752, NP_116141

UniProt: Q96IT1