EEA1 anticorps (N-Term)

N° du produit ABIN2779263

Cet anticorps Lapin Polyclonal détecte spécifiquement EEA1 dans WB, IHC et IP. Il présente une réactivité envers Humain, Souris, Rat, Chien, Lapin, Cheval, Boeuf (Vache) et Cobaye et a été mentionné dans 1 publication.

Aperçu rapide pour EEA1 anticorps (N-Term) (ABIN2779263)

Antigène: EEA1 (Early Endosome Antigen 1 (EEA1))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cheval, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EEA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-EEA1 anticorps

Épitope: N-Term

Séquence: LTENLLKKEQ DYTKLEEKHN EESVSKKNIQ ATLHQKDLDC QQLQSRLSAS

Homologie: Cow: 92%, Dog: 75%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against EEA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human EEA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1411 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-EEA1 (ABIN2779263)

Cebrian, Croce, Guerrero, Blanchard, Mayorga: "Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells." dans: EMBO reports, Vol. 17, Issue 12, pp. 1753-1765, (2016) (PubMed).

Détails sur EEA1

Antigène: EEA1 (Early Endosome Antigen 1 (EEA1))

Autre désignation: EEA1

Sujet: EEA1 is involved in neuronal synaptic vesicle function and axonal transport and growth. EEA1 may undergo calcium-dependent conformational changes that are required for binding to SNAP-25.
Alias Symbols: MST105, ZFYVE2, MSTP105
Protein Interaction Partner: UBC, RNF2, BMI1, CFTR, ERBB2, VCP, EEA1, RAB5A, TNK2, RABEP1, RABGEF1, PDCD6IP, PXK, HDAC6, ZFYVE16, USO1, STX6, RAB22A, STX12, TOM1, RAB5C, MAPK14, RAB5B, IGF1R, NSF,
Protein Size: 1411

Poids moléculaire: 162 kDa

ID gène: 8411

NCBI Accession: NM_003566, NP_003557

UniProt: Q15075

Pathways: Toll-Like Receptors Cascades