RAD17 anticorps (N-Term)

N° du produit ABIN2779342

Cet anticorps Lapin Polyclonal détecte spécifiquement RAD17 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Chien, Boeuf (Vache), Porc, Cheval et Lapin.

Aperçu rapide pour RAD17 anticorps (N-Term) (ABIN2779342)

Antigène: RAD17

Reactivité: Humain, Rat, Chien, Boeuf (Vache), Porc, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD17 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RAD17 anticorps

Épitope: N-Term

Fonction: RAD17 Antibody - N-terminal region

Séquence: MNQVTDWVDP SFDDFLECSG VSTITATSLG VNNSSHRRKN GPSTLESSRF

Homologie: Cow: 89%, Dog: 100%, Horse: 92%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 89%

Attributs du produit: This is a rabbit polyclonal antibody against RAD17. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RAD17

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30546-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RAD17

Antigène: RAD17

Autre désignation: RAD17

Sujet:

Background Information: RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation.

Gene Name: RAD17 homolog (S. pombe)

Alternative Symbols: CCYC, R24L, RAD24, HRAD17, RAD17SP

Protein Name: Cell cycle checkpoint protein RAD17

Poids moléculaire: 76kDa

ID gène: 5884

NCBI Accession: NP_002864

UniProt: O75943