HAND2 anticorps (C-Term)

N° du produit ABIN2779346

Détail du produit anti-HAND2 anticorps

Antigène: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Cheval, Boeuf (Vache), Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAND2 est non-conjugé

Application: Western Blotting (WB)

Séquence: DQNGEAEAFK AEIKKTDVKE EKRKKELNEI LKSTVSSNDK KTKGRTGWPQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 87%

Attributs du produit: This is a rabbit polyclonal antibody against Hand2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 217 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HAND2

Antigène: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Autre désignation: Hand2 (HAND2 Produits)

Synonymes: anticorps DHAND2, anticorps Hed, anticorps Thing2, anticorps bHLHa26, anticorps dHand, anticorps dhand2, anticorps hand2, anticorps xhand2, anticorps hand2-b, anticorps Hand2', anticorps dHAND, anticorps HAND2, anticorps hed, anticorps dhand, anticorps thing2, anticorps LOC100218345, anticorps AI225906, anticorps AI661148, anticorps Ehand2, anticorps Th2, anticorps zdHAND, anticorps zgc:103415, anticorps Hand2, anticorps heart and neural crest derivatives expressed 2, anticorps heart and neural crest derivatives expressed 2 L homeolog, anticorps heart and neural crest derivatives expressed 2 S homeolog, anticorps HAND2, anticorps Hand2, anticorps hand2.L, anticorps hand2.S, anticorps hand2

Sujet: Hand2 is essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. It is required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. It plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Hand2 is involved in the development of branchial arches, which give rise to unique structures in the head and neck.
Alias Symbols: AI225906, AI661148, Ehand2, Hed, Th2, Thing2, bHLHa26, dHAND
Protein Interaction Partner: Nkx2-5, Hand1, Tcf3, Tcf4, Tcf12, Hoxd13, Twist1,
Protein Size: 217

Poids moléculaire: 24 kDa

ID gène: 15111

NCBI Accession: NM_010402, NP_034532

UniProt: Q61039

Pathways: Tube Formation, Feeding Behaviour