CLK4 anticorps (N-Term)

N° du produit ABIN2779361

Il existe 1 publication pour ce produit. L’anticorps anti-CLK4 Polyclonal Lapin est utilisé pour la détection de CLK4 dans des échantillons de Souris, Humain, Chien, Cobaye, Lapin, Rat, Boeuf (Vache), Cheval et Saccharomyces cerevisiae. Il a été validé pour WB.

Aperçu rapide pour CLK4 anticorps (N-Term) (ABIN2779361)

Antigène: CLK4 (CDC-Like Kinase 4 (CLK4))

Reactivité: Souris, Humain, Chien, Cobaye, Lapin, Rat, Boeuf (Vache), Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLK4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CLK4 anticorps

Épitope: N-Term

Fonction: CLK4 Antibody - N-terminal region

Séquence: RSRRSSPKRK RNRHCSSHQS RSKSHRRKRS RSIEDDEEGH LICQSGDVLR

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 91%

Attributs du produit: This is a rabbit polyclonal antibody against CLK4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CLK4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30645-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CLK4 (ABIN2779361)

Eisenreich, Zakrzewicz, Huber, Thierbach, Pepke, Goldin-Lang, Schultheiss, Pries, Rauch: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." dans: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).

Détails sur CLK4

Antigène: CLK4 (CDC-Like Kinase 4 (CLK4))

Autre désignation: CLK4

Sujet:

Background Information: The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.

Gene Name: CDC-like kinase 4

Alternative Symbols: DKFZp686A20267

Protein Name: Dual specificity protein kinase CLK4

Poids moléculaire: 57

ID gène: 57396

NCBI Accession: NP_065717

UniProt: Q9HAZ1