CCBP2 anticorps (N-Term)

N° du produit ABIN2779383

L’anticorps anti-CCBP2 Polyclonal Lapin est utilisé pour la détection de CCBP2 dans des échantillons de Humain et Lapin. Il a été validé pour WB et IHC.

Aperçu rapide pour CCBP2 anticorps (N-Term) (ABIN2779383)

Antigène: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Reactivité: Humain, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCBP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CCBP2 anticorps

Épitope: N-Term

Fonction: CCBP2 Antibody - N-terminal region

Séquence: MAATASPQPL ATEDADSENS SFYYYDYLDE VAFMLCRKDA VVSFGKVFLP

Homologie: Human: 100%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CCBP2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CCBP2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096886

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CCBP2

Antigène: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Autre désignation: CCBP2

Sujet:

Background Information: CCBP2 is a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown.This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Gene Name: Chemokine binding protein 2

Alternative Symbols: D6, hD6, CCR9, CCBP2, CCR10, CMKBR9

Protein Name: Chemokine-binding protein 2

Poids moléculaire: 43kDa

ID gène: 1238

NCBI Accession: NP_001287

UniProt: O00590