PDX1 anticorps (N-Term)

N° du produit ABIN2779403

Détail du produit anti-PDX1 anticorps

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDX1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LYMGRQPPPP PPPQFTSSLG SLEQGSPPDI SPYEVPPLAS DDPAGAHLHH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Pdx1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 284 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDX1

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Autre désignation: Pdx1 (PDX1 Produits)

Synonymes: anticorps GSF, anticorps IDX-1, anticorps IPF1, anticorps IUF1, anticorps MODY4, anticorps PDX-1, anticorps STF-1, anticorps ipf1, anticorps PDX1, anticorps IPF-1, anticorps Ipf1, anticorps Mody4, anticorps pdx-1, anticorps Idx1, anticorps Stf1, anticorps zgc:100874, anticorps XlHbox-8, anticorps xlhbox8, anticorps pancreatic and duodenal homeobox 1, anticorps pancreatic and duodenal homeobox 1 S homeolog, anticorps PDX1, anticorps pdx1, anticorps Pdx1, anticorps pdx1.S

Sujet: Pdx1 activates insulin and somatostatin gene transcription. It is a key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. It binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
Alias Symbols: IDX-1, IPF-1, Ipf1, Mody4, STF-1, pdx-1
Protein Interaction Partner: Pcif1, Meis1, Hdac1, Hdac2, Ins1, Iapp, Spop, Pax4,
Protein Size: 284

Poids moléculaire: 31 kDa

ID gène: 18609

NCBI Accession: NM_008814, NP_032840

UniProt: P52946

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location