TRIM23 anticorps (N-Term)

N° du produit ABIN2779407

Cet anticorps anti-TRIM23 Polyclonal Lapin (ABIN2779407) détecte spécifiquement TRIM23 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Cobaye, Cheval, Lapin et Boeuf (Vache).

Aperçu rapide pour TRIM23 anticorps (N-Term) (ABIN2779407)

Antigène: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM23 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRIM23 anticorps

Épitope: N-Term

Fonction: TRIM23 Antibody - N-terminal region

Séquence: CPFDRQVTDL GDSGVWGLKK NFALLELLER LQNGPIGQYG AAEESIGISG

Homologie: Cow: 90%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Rabbit: 85%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against TRIM23. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM23

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114639

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRIM23

Antigène: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Autre désignation: TRIM23

Sujet:

Background Information: TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.

Gene Name: Tripartite motif containing 23

Alternative Symbols: ARD1, ARFD1, RNF46

Protein Name: E3 ubiquitin-protein ligase TRIM23

Poids moléculaire: 64kDa

ID gène: 373

NCBI Accession: NP_001647

UniProt: P36406