SMAD5 anticorps (Middle Region)

N° du produit ABIN2779414

Cet anticorps Lapin Polyclonal détecte spécifiquement SMAD5 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Poisson zèbre (Danio rerio), Mouton, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour SMAD5 anticorps (Middle Region) (ABIN2779414)

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Mouton, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SMAD5 anticorps

Épitope: Middle Region

Séquence: YPPSPASSTY PNSPASSGPG SPFQLPADTP PPAYMPPDDQ MGQDNSQPMD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SMAD5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SMAD5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 465 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMAD5

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Autre désignation: SMAD5

Sujet: SMAD5 undergoes copy number gain and increased expression, rather than loss of expression, and therefore does not act as a tumor-suppressor gene in hepatocellular carcinoma. Up-regulated Smad5 mediates apoptosis of gastric epithelial cells induced by Helicobacter pylori infection.
Alias Symbols: DWFC, JV5-1, MADH5
Protein Interaction Partner: UBC, SUMO1, HECW2, HBG2, BCAT1, SOX5, SNRPA, SNRNP70, SFPQ, RYR2, RBM4, PTPN12, PSMD11, NEDD4, SMAD4, SMAD1, ANKRD13A, PPIL4, SOX7, SMURF2, SMURF1, MTMR10, CHMP3, CXXC5, SF3B1, U2AF2, PNKP, WWP1, NAA20, EPN1, SMAD3, SMAD2, PAX6, COPS5, HGS, EP300, ELAVL1,
Protein Size: 465

Poids moléculaire: 51 kDa

ID gène: 4090

NCBI Accession: NM_005903, NP_005894

UniProt: Q99717