ASCL2 anticorps (Middle Region)

N° du produit ABIN2779425

Cet anticorps Lapin Polyclonal détecte spécifiquement ASCL2 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin et Poisson zèbre (Danio rerio).Il a été cité dans 1 publication.

Aperçu rapide pour ASCL2 anticorps (Middle Region) (ABIN2779425)

Antigène: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASCL2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ASCL2 anticorps

Épitope: Middle Region

Fonction: ASCL2 Antibody - middle region

Séquence: QALRQHVPHG GASKKLSKVE TLRSAVEYIR ALQRLLAEHD AVRNALAGGL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 100%, Zebrafish: 77%

Attributs du produit: This is a rabbit polyclonal antibody against ASCL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ASCL2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32025-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ASCL2 (ABIN2779425)

Schwitalla, Fingerle, Cammareri, Nebelsiek, Göktuna, Ziegler, Canli, Heijmans, Huels, Moreaux, Rupec, Gerhard, Schmid, Barker, Clevers, Lang, Neumann, Kirchner, Taketo, van den Brink, Sansom, Arkan et al.: "Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties. ..." dans: Cell, Vol. 152, Issue 1-2, pp. 25-38, (2013) (PubMed).

Détails sur ASCL2

Antigène: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Autre désignation: ASCL2

Sujet:

Background Information: AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1649 BC028140.1 1-1649 1650-1864 BC057801.1 1286-1500

Gene Name: Achaete-scute complex homolog 2 (Drosophila)

Alternative Symbols: ASH2, HASH2, MASH2, bHLHa45

Protein Name: Achaete-scute homolog 2

Poids moléculaire: 20 kDa

ID gène: 430

NCBI Accession: NP_005161

UniProt: Q99929

Pathways: Stem Cell Maintenance