MTF1 anticorps (C-Term)

N° du produit ABIN2779426

Détail du produit anti-MTF1 anticorps

Antigène: MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))

Épitope: C-Term

Reactivité: Humain, Souris, Chien, Rat, Boeuf (Vache), Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTF1 est non-conjugé

Application: Western Blotting (WB)

Séquence: QSSLVMGEQN LQWILNGATS SPQNQEQIQQ ASKVEKVFFT TAVPVASSPG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MTF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human MTF1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 753 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MTF1

Antigène: MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))

Autre désignation: MTF1 (MTF1 Produits)

Synonymes: anticorps MTF-1, anticorps MTF1, anticorps mtf1, anticorps MGC86485, anticorps Thyls, anticorps ZRF, anticorps metal regulatory transcription factor 1, anticorps metal-regulatory transcription factor 1, anticorps metal-regulatory transcription factor 1 L homeolog, anticorps metal response element binding transcription factor 1, anticorps MTF1, anticorps mtf1, anticorps mtf1.L, anticorps Mtf1

Sujet: The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.
Alias Symbols: ZRF, MTF-1
Protein Interaction Partner: AP1M1, EP300, CREBBP, MT1G,
Protein Size: 753

Poids moléculaire: 81 kDa

ID gène: 4520

NCBI Accession: NM_005955, NP_005946

UniProt: Q14872