NKX3-1 anticorps (Middle Region)

N° du produit ABIN2779438

Cet anticorps Lapin Polyclonal détecte spécifiquement NKX3-1 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour NKX3-1 anticorps (Middle Region) (ABIN2779438)

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKX3-1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NKX3-1 anticorps

Épitope: Middle Region

Fonction: NKX3-1 Antibody - middle region

Séquence: KRKQLSSELG DLEKHSSLPA LKEEAFSRAS LVSVYNSYPY YPYLYCVGSW

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 85%, Horse: 79%, Human: 100%, Rabbit: 79%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against NKX3-1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NKX3-1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8106552

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur NKX3-1

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Autre désignation: NKX3-1

Sujet:

Background Information: The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: NK3 homeobox 1

Alternative Symbols: NKX3, BAPX2, NKX3A, NKX3.1

Protein Name: Homeobox protein Nkx-3.1

Poids moléculaire: 26kDa

ID gène: 4824

NCBI Accession: NP_006158

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus