DVL2 anticorps (N-Term)

N° du produit ABIN2779458

Cet anticorps anti-DVL2 est un anticorps Lapin Polyclonal détectant DVL2 dans WB et IHC. Adapté pour Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Saccharomyces cerevisiae. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour DVL2 anticorps (N-Term) (ABIN2779458)

Antigène: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DVL2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-DVL2 anticorps

Épitope: N-Term

Séquence: AGSSTGGGGV GETKVIYHLD EEETPYLVKI PVPAERITLG DFKSVLQRPA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DVL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DVL2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 736 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DVL2 (ABIN2779458)

Lee, Zhao, Moon, Yoon, Kim, An, Kwon, Hwang, Choi, Shim, Kim, Yang: "Differential involvement of GABA system in mediating behavioral and neurochemical effect of acupuncture in ethanol-withdrawn rats." dans: Neuroscience letters, Vol. 443, Issue 3, pp. 213-7, (2008) (PubMed).

Détails sur DVL2

Antigène: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Autre désignation: DVL2

Sujet: DVL2 is a member of the dishevelled (dsh) protein family. It is a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: UBC, NUMA1, IQGAP1, DVL3, DVL1, RNF185, WWOX, SQSTM1, IRS2, IRS1, TARS, GABARAPL1, CSNK1E, OTULIN, TP53, LYN, Smurf2, PLA2G12A, CTBP2, LRRK2, ATN1, RBFOX1, ITCH, ELAVL1, NHLRC1, MAP1LC3A, GABARAP, VHL, SIRT1, VANGL1, TCEB3B, CPSF7, SNF8, PPM1A, POLI, DYNL
Protein Size: 736

Poids moléculaire: 79 kDa

ID gène: 1856

NCBI Accession: NM_004422, NP_004413

UniProt: O14641

Pathways: Tube Formation