SPIC anticorps (C-Term)

N° du produit ABIN2779513

Cet anticorps Lapin Polyclonal détecte spécifiquement SPIC dans WB. Il présente une réactivité envers Humain, Souris, Boeuf (Vache), Cheval, Chien, Cobaye, Rat, Lapin, Porc et Poisson zèbre (Danio rerio) et a été mentionné dans 1 publication.

Aperçu rapide pour SPIC anticorps (C-Term) (ABIN2779513)

Antigène: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Reactivité: Humain, Souris, Boeuf (Vache), Cheval, Chien, Cobaye, Rat, Lapin, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPIC est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPIC anticorps

Épitope: C-Term

Séquence: EKLAELWGKR KGNRKTMTYQ KMARALRNYG RSGEITKIRR KLTYQFSEAI

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against SPIC. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 248 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SPIC (ABIN2779513)

Zhu, Schweitzer, Romer, Sulentic, DeKoter: "Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling." dans: European journal of immunology, Vol. 38, Issue 9, pp. 2587-99, (2008) (PubMed).

Détails sur SPIC

Antigène: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Autre désignation: SPIC

Sujet: SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC Regulates VCAM1 gene expression.
Alias Symbols: MGC40611, SPI-C
Protein Interaction Partner: APP,
Protein Size: 248

Poids moléculaire: 29 kDa

ID gène: 121599

NCBI Accession: NM_152323, NP_689536

UniProt: Q8N5J4