ESRRA anticorps (C-Term)

N° du produit ABIN2779529

Détail du produit anti-ESRRA anticorps

Antigène: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESRRA est non-conjugé

Application: Western Blotting (WB)

Séquence: AGRAGPGGGA ERRRAGRLLL TLPLLRQTAG KVLAHFYGVK LEGKVPMHKL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Esrra. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 422 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ESRRA

Antigène: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Autre désignation: Esrra (ESRRA Produits)

Synonymes: anticorps err1, anticorps erra, anticorps esrral, anticorps erralpha, anticorps nr3b1, anticorps MGC80854, anticorps ESRRA, anticorps esrl1, anticorps LOC100125507, anticorps ERRalpha, anticorps Err1, anticorps Estrra, anticorps Nr3b1, anticorps Errra, anticorps ERR1, anticorps ERRa, anticorps ESRL1, anticorps NR3B1, anticorps ESTRRA, anticorps estrogen-related receptor alpha, anticorps estrogen related receptor alpha L homeolog, anticorps estrogen related receptor alpha, anticorps catsper channel auxiliary subunit zeta, anticorps estrogen related receptor, alpha, anticorps esrra, anticorps esrra.L, anticorps ESRRA, anticorps LOC100125507, anticorps CATSPERZ, anticorps Esrra

Sujet: Esrra binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. It can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. It binds to the C1 region of the lactoferrin gene promoter. It requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
Alias Symbols: ERRalpha, Err1, Estrra, Nr3b1
Protein Interaction Partner: Ubc, Sirt1, Hdac8, Kat2b, Crebzf, Esrrb, Ppargc1a,
Protein Size: 422

Poids moléculaire: 45 kDa

ID gène: 26379

NCBI Accession: NM_007953, NP_031979

UniProt: O08580

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha