SNW1 anticorps (N-Term)

N° du produit ABIN182523

Cet anticorps anti-SNW1 Polyclonal Lapin (ABIN182523) détecte spécifiquement SNW1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Chien, Rat, Boeuf (Vache), Cheval, Porc, Lapin, Cobaye et Saccharomyces cerevisiae.

Aperçu rapide pour SNW1 anticorps (N-Term) (ABIN182523)

Antigène: SNW1 (SNW Domain Containing 1 (SNW1))

Reactivité: Humain, Souris, Chien, Rat, Boeuf (Vache), Cheval, Porc, Lapin, Cobaye, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNW1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SNW1 anticorps

Épitope: N-Term

Séquence: RQGQSKDKVI YSKYTDLVPK EVMNADDPDL QRPDEEAIKE ITEKTRVALE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%

Attributs du produit: This is a rabbit polyclonal antibody against SKIIP. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SKIIP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 536 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SNW1

Antigène: SNW1 (SNW Domain Containing 1 (SNW1))

Autre désignation: SKIIP

Sujet: SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
Alias Symbols: Bx42, SKIP, Prp45, SKIIP, PRPF45, NCOA-62
Protein Interaction Partner: TRAF1, GOLGA2, KRT40, LZTS2, RINT1, TEX11, CEP55, PPIL1, TFIP11, MTUS2, IKZF1, TP53, TUBGCP3, AURKB, UBC, SUZ12, RNF2, BMI1, HECW2, HDAC11, Dlg4, TTC14, ZNF830, SNIP1, CXorf56, XAB2, CTNNBL1, SART1, NHP2L1, MFAP1, EIF4A3, MAGOH, DHX15, DDX5, PABPC1, SKIV2
Protein Size: 536

Poids moléculaire: 61 kDa

ID gène: 22938

NCBI Accession: NM_012245, NP_036377

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway