HNF1B anticorps (N-Term)

N° du produit ABIN2779562

Détail du produit anti-HNF1B anticorps

Antigène: HNF1B (HNF1 Homeobox B (HNF1B))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNF1B est non-conjugé

Application: Western Blotting (WB)

Séquence: LETLPLSPGS GAEPDTKPVF HTLTNGHAKG RLSGDEGSED GDDYDTPPIL

Specificité: 100 % specific to all three isoforms of HNF1B (61, 58, 45kD).

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HNF1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 399 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HNF1B

Antigène: HNF1B (HNF1 Homeobox B (HNF1B))

Autre désignation: HNF1B (HNF1B Produits)

Synonymes: anticorps FJHN, anticorps HNF-1B, anticorps HNF1beta, anticorps HNF2, anticorps HPC11, anticorps LF-B3, anticorps LFB3, anticorps MODY5, anticorps TCF-2, anticorps TCF2, anticorps VHNF1, anticorps HNF-1b, anticorps HNF1B, anticorps AI385728, anticorps AI987804, anticorps HNF-1Beta, anticorps Hnf1beta, anticorps Tcf-2, anticorps Tcf2, anticorps vHNF1, anticorps vHNF-1, anticorps chunp6877, anticorps hnf1b, anticorps mst, anticorps tcf2, anticorps vhnf1, anticorps lfb3, anticorps hnf-1beta, anticorps hnf1-beta, anticorps hnf1beta, anticorps HNF1g, anticorps wu:fc23f06, anticorps HNF1 homeobox B, anticorps HNF1 homeobox Ba, anticorps HNF1 homeobox B S homeolog, anticorps HNF1 homeobox B L homeolog, anticorps HNF1 homeobox Bb, anticorps HNF1B, anticorps Hnf1b, anticorps hnf1ba, anticorps hnf1b.S, anticorps hnf1b.L, anticorps hnf1bb

Sujet: Hepatocyte Nuclear Factor 1-. (HNF-1., Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1, depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.
Alias Symbols: FJHN, HNF1beta, HNF2, LFB3, MODY5, TCF2, VHNF1, HPC11, LF-B3
Protein Interaction Partner: HIST1H3A, PCBD1, CREBBP, HNF1A, ATF1, CREB1,
Protein Size: 399

Poids moléculaire: 45 kDa

ID gène: 6928

NCBI Accession: NM_006481, NP_006472

UniProt: P35680

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation