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T-Box 19 anticorps (Middle Region)

TBX19 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Porc WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2779591
  • Antigène Voir toutes T-Box 19 (TBX19) Anticorps
    T-Box 19 (TBX19)
    Épitope
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Porc
    Hôte
    • 10
    • 1
    Lapin
    Clonalité
    • 9
    • 2
    Polyclonal
    Conjugué
    • 11
    Cet anticorp T-Box 19 est non-conjugé
    Application
    • 11
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    IKYNPFAKAF LDAKERNHLR DVPEAISESQ HVTYSHLGGW IFSNPDGVCT
    Homologie
    Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 77%
    Attributs du produit
    This is a rabbit polyclonal antibody against TBX19. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human TBX19
    Top Product
    Discover our top product TBX19 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 448 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    T-Box 19 (TBX19)
    Autre désignation
    TBX19 (TBX19 Produits)
    Synonymes
    anticorps TBX19, anticorps TBS19, anticorps TPIT, anticorps dJ747L4.1, anticorps CH-TBXT, anticorps TBXT, anticorps AU019250, anticorps D1Ertd754e, anticorps Tpit, anticorps T-box 19, anticorps TBX19, anticorps Tbx19
    Sujet
    TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: FLJ26302, FLJ34543, TBS 19, TBS19, TPIT, dJ747L4.1
    Protein Interaction Partner: NR5A1,
    Protein Size: 448
    Poids moléculaire
    48 kDa
    ID gène
    9095
    NCBI Accession
    NM_005149, NP_005140
    UniProt
    O60806
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