SIX Homeobox 1 anticorps (Middle Region)

N° du produit ABIN2779599

Détail du produit anti-SIX Homeobox 1 anticorps

Antigène: SIX Homeobox 1 (SIX1)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache), Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIX Homeobox 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SEEEFSPPQS PDQNSVLLLQ GNMGHARSSN YSLPGLTASQ PSHGLQTHQH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SIX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SIX1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 284 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SIX Homeobox 1 (ABIN2779599)

Lee, Kim, Ryu, Lee, Yang, Jeong, Kim, Lee, Kim, Hajjar, Park: "Transcription coactivator Eya2 is a critical regulator of physiological hypertrophy." dans: Journal of molecular and cellular cardiology, Vol. 52, Issue 3, pp. 718-26, (2012) (PubMed).

Détails sur SIX Homeobox 1

Antigène: SIX Homeobox 1 (SIX1)

Autre désignation: SIX1 (SIX1 Produits)

Synonymes: anticorps BOS3, anticorps DFNA23, anticorps TIP39, anticorps BB138287, anticorps six1b, anticorps six2, anticorps zgc:92332, anticorps XSix1, anticorps six1, anticorps zgc:77345, anticorps SIX homeobox 1, anticorps sine oculis-related homeobox 1, anticorps SIX homeobox 1a, anticorps SIX homeobox 1 L homeolog, anticorps SIX homeobox 1b, anticorps SIX1, anticorps Six1, anticorps six1a, anticorps six1.L, anticorps six1b

Sujet: SIX1 is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3).The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BOS3, DFNA23, TIP39
Protein Interaction Partner: AES, VTN, FZR1, UBC, SKI, CCDC85B, DACH1, EYA3, EYA2, MDFI, EYA4, EYA1, SIX1, TLE1,
Protein Size: 284

Poids moléculaire: 32 kDa

ID gène: 6495

NCBI Accession: NM_005982, NP_005973

UniProt: Q15475

Pathways: Sensory Perception of Sound, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development