SIRT2 anticorps (N-Term)

N° du produit ABIN2779604

Cet anticorps Lapin Polyclonal détecte spécifiquement SIRT2 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Lapin, Chien, Cobaye, Boeuf (Vache), Porc, Cheval et Saccharomyces cerevisiae et a été mentionné dans 1 publication.

Aperçu rapide pour SIRT2 anticorps (N-Term) (ABIN2779604)

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Reactivité: Humain, Rat, Souris, Lapin, Chien, Cobaye, Boeuf (Vache), Porc, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SIRT2 anticorps

Épitope: N-Term

Séquence: MAEPDPSHPL ETQAGKVQEA QDSDSDSEGG AAGGEADMDF LRNLFSQTLS

Homologie: Cow: 92%, Dog: 82%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 100%, Rat: 77%, Yeast: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SIRT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 389 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SIRT2 (ABIN2779604)

Benavente, Schnell, Jacobson: "Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin." dans: PLoS ONE, Vol. 7, Issue 7, pp. e42276, (2012) (PubMed).

Détails sur SIRT2

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Autre désignation: SIRT2

Sujet: SIRT2 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by SIRT2 is included in class I of the sirtuin family.
Alias Symbols: SIR2, SIR2L, SIR2L2
Protein Interaction Partner: ACLY, SIRT1, UBC, ING1, EP300, CBLB, CBL, XPO1, CDC20, FZR1, RUNX3, PCK1, FOXO1, HDAC6, tat, RBP1, HIST1H3A, NUDT21, PAPOLA, DNAJB8, DNAJB6, SP140, KAT2B, CDC14B, KAT2A, TUBA4A, HOXA10, TUBB, KRT78, RTN4, PHB2, SPOP, ELL, SARS, GYS1,
Protein Size: 389

Poids moléculaire: 43 kDa

ID gène: 22933

NCBI Accession: NM_012237, NP_036369

UniProt: Q8IXJ6