SIRT2 anticorps (N-Term)

N° du produit ABIN2779604

Cet anticorps Lapin Polyclonal détecte spécifiquement SIRT2 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Lapin, Cobaye, Chien, Boeuf (Vache), Porc, Cheval et Saccharomyces cerevisiae.Il a été cité dans 1 publication.

Aperçu rapide pour SIRT2 anticorps (N-Term) (ABIN2779604)

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Reactivité: Humain, Rat, Souris, Lapin, Cobaye, Chien, Boeuf (Vache), Porc, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SIRT2 anticorps

Épitope: N-Term

Fonction: SIRT2 Antibody - N-terminal region

Séquence: MAEPDPSHPL ETQAGKVQEA QDSDSDSEGG AAGGEADMDF LRNLFSQTLS

Homologie: Cow: 92%, Dog: 82%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 100%, Rat: 77%, Yeast: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SIRT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111799

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SIRT2 (ABIN2779604)

Benavente, Schnell, Jacobson: "Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin." dans: PLoS ONE, Vol. 7, Issue 7, pp. e42276, (2012) (PubMed).

Détails sur SIRT2

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Autre désignation: SIRT2

Sujet:

Background Information: SIRT2 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by SIRT2 is included in class I of the sirtuin family.

Gene Name: Sirtuin 2

Alternative Symbols: SIR2, SIR2L, SIR2L2

Protein Name: NAD-dependent protein deacetylase sirtuin-2

Poids moléculaire: 43kDa

ID gène: 22933

NCBI Accession: NP_036369

UniProt: Q8IXJ6