SIRT2 anticorps (C-Term)
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- Antigène Voir toutes SIRT2 Anticorps
- SIRT2 (Sirtuin 2 (SIRT2))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris, Lapin, Chien, Cobaye, Boeuf (Vache), Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SIRT2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- DVAWLGECDQ GCLALAELLG WKKELEDLVR REHASIDAQS GAGVPNPSTS
- Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%, Zebrafish: 75%
- Attributs du produit
- This is a rabbit polyclonal antibody against SIRT2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT2
- Top Product
- Discover our top product SIRT2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 352 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SIRT2 (Sirtuin 2 (SIRT2))
- Autre désignation
- SIRT2 (SIRT2 Produits)
- Sujet
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SIRT2 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT2 is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene.
Alias Symbols: SIR2, SIR2L, SIR2L2
Protein Interaction Partner: ACLY, SIRT1, UBC, ING1, EP300, CBLB, CBL, XPO1, CDC20, FZR1, RUNX3, PCK1, FOXO1, HDAC6, tat, RBP1, HIST1H3A, NUDT21, PAPOLA, DNAJB8, DNAJB6, SP140, KAT2B, CDC14B, KAT2A, TUBA4A, HOXA10, TUBB, KRT78, RTN4, PHB2, SPOP, ELL, SARS, GYS1,
Protein Size: 352 - Poids moléculaire
- 40 kDa
- ID gène
- 22933
- NCBI Accession
- NM_030593, NP_085096
- UniProt
- Q8IXJ6
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