EHMT2 anticorps (N-Term)
Aperçu rapide pour EHMT2 anticorps (N-Term) (ABIN2779680)
Antigène
Voir toutes EHMT2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- EHMT2 Antibody - N-terminal region
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Séquence
- VQSLAMRLLS MPGAQGAAAA GSEPPPATTS PEGQPKVHRA RKTMSKPGNG
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Homologie
- Cow: 92%, Dog: 86%, Guinea Pig: 93%, Horse: 77%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against EHMT2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human EHMT2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32493-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells." dans: PLoS ONE, Vol. 3, Issue 4, pp. e2037, (2008) (PubMed).
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- EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))
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Autre désignation
- EHMT2
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Sujet
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Background Information: A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster, it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. These genes are all within the human major histocompatibility complex class III region. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but a recent publication shows that there is only a single gene. The protein encoded by this gene is thought to be involved in intracellular protein-protein interaction.A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster, it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. These genes are all within the human major histocompatibility complex class III region. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but a recent publication shows that there is only a single gene. The protein encoded by this gene is thought to be involved in intracellular protein-protein interaction. There are three alternatively spliced transcript variants of this gene but only two are fully described.
Gene Name: Euchromatic histone-lysine N-methyltransferase 2
Alternative Symbols: G9A, BAT8, GAT8, NG36, KMT1C, C6orf30
Protein Name: Histone-lysine N-methyltransferase EHMT2
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Poids moléculaire
- 132kDa
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ID gène
- 10919
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NCBI Accession
- NP_006700
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UniProt
- Q96KQ7
Antigène
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