SND1 anticorps (N-Term)

N° du produit ABIN2779724

Cet anticorps anti-SND1 est un anticorps Lapin Polyclonal détectant SND1 dans WB et IHC. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cobaye et Cheval.

Aperçu rapide pour SND1 anticorps (N-Term) (ABIN2779724)

Antigène: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SND1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SND1 anticorps

Épitope: N-Term

Séquence: LPDYYLVTVM LSGIKCPTFR READGSETPE PFAAEAKFFT ESRLLQRDVQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SND1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SND1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 885 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SND1

Antigène: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Autre désignation: SND1

Sujet: SND1 was originally characterized as a transcriptional coactivator for Epstein-Barr virus nuclear antigen 2. It is a STAT6 TAD interacting protein containing staphylococcal nuclease (SN)-like domain and tudor domain. p100 . The interaction is mediated by the TAD domain of STAT6 and the SN-like domain of SND1. SND1 associates with the large subunit of RNA polymerase II and is mediating interaction between STAT6 and RNA polymerase II. It was identified as a novel coactivator for STAT6 and suggest its functions as a bridging factor between STAT6 and the basal transcription machinery
Alias Symbols: p100, TDRD11
Protein Interaction Partner: HUWE1, RAPGEF2, UBC, SUMO2, MDM2, LIN28A, SHFM1, DDX3X, EIF3CL, RPL35, RPS27, RPS26, RPS16, RPS11, RPS9, RPS6, RPS3A, RPS2, RPL23A, HNRNPU, TARDBP, UBD, RNU4-1, RNU5A-1, RNU6-1, PRPF8, RNU2-1, RNU1-1, G3BP1, VCAM1, MAK, ITGA4, FN1, CSNK2A1, SSR3, SRSF3, R
Protein Size: 885

Poids moléculaire: 100 kDa

ID gène: 27044

NCBI Accession: NM_014390, NP_055205

UniProt: Q7KZF4