Arx anticorps (Middle Region)

N° du produit ABIN2779819

Cet anticorps anti-Arx est un anticorps Lapin Polyclonal détectant Arx dans WB. Adapté pour Humain, Souris, Rat, Chien, Lapin, Cobaye et Cheval. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour Arx anticorps (Middle Region) (ABIN2779819)

Antigène: Arx (ARX) (Aristaless Related Homeobox (ARX))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Arx est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Arx anticorps

Épitope: Middle Region

Séquence: TGAEDDEEEL LEDEEDEEEE EELLEDDDEE LLEDDARALL KEPRRCSVAT

Homologie: Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 93%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ARX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of mouse ARX

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 564 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Arx (ABIN2779819)

Price, Yoo, Burgess, Deng, Hrachovy, Frost, Noebels et al.: "A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral ..." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 27, pp. 8752-63, (2009) (PubMed).

Condomines, Hose, Rème, Requirand, Hundemer, Schoenhals, Goldschmidt, Klein: "Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 2, pp. 832-40, (2009) (PubMed).

Détails sur Arx

Antigène: Arx (ARX) (Aristaless Related Homeobox (ARX))

Autre désignation: ARX

Sujet: ARX (Aristaless-related genes), a subset of the Paired-related homeobox genes, is a group of regulators of essential events during vertebrate embryogenesis. Arx was highly conserved between mouse and zebrafish. Studies have disclosed its neuromeric expression in the forebrain and longitudinal expression in the floor plate in mouse and zebrafish. It is also expressed in the dorsal telencephalon (presumptive cerebral cortex) of mouse embryos.
Protein Size: 564

Poids moléculaire: 58 kDa

ID gène: 11878

NCBI Accession: NM_007492, NP_031518

UniProt: O35085