FOXA3 anticorps (C-Term)

N° du produit ABIN2779850

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXA3 dans WB. Il présente une réactivité envers Humain, Chien, Souris, Rat, Boeuf (Vache), Cobaye, Cheval et Porc.

Aperçu rapide pour FOXA3 anticorps (C-Term) (ABIN2779850)

Antigène: FOXA3 (Forkhead Box A3 (FOXA3))

Reactivité: Humain, Chien, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXA3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FOXA3 anticorps

Épitope: C-Term

Séquence: YNFNHPFSIN NLMSEQTSTP SKLDVGFGGY GAESGEPGVY YQSLYSRSLL

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 86%, Mouse: 100%, Pig: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Foxa3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the c terminal region of mouse Foxa3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 353 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FOXA3

Antigène: FOXA3 (Forkhead Box A3 (FOXA3))

Autre désignation: Foxa3

Sujet: Foxa3 is a transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Foxa3 is originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Foxa3 interacts with the cis-acting regulatory regions of these genes.Foxa3 is involved in glucose homeostasis, activates GLUT2 transcription and regulation of neuronal-specific transcription. Foxa3 is also involved in regulation of spermatogenesis, required for the maintenance of the testicular germ cell population and male fertility.
Alias Symbols: Hnf-3g, Hnf3g, Tcf-3g, Tcf3g
Protein Size: 353

Poids moléculaire: 37 kDa

ID gène: 15377

NCBI Accession: NM_008260, NP_032286

UniProt: P35584

Pathways: Carbohydrate Homeostasis