IRF1 anticorps (C-Term)

N° du produit ABIN2779860

Détail du produit anti-IRF1 anticorps

Antigène: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF1 est non-conjugé

Application: Western Blotting (WB)

Séquence: HIDGKGYLLN EPGTQLSSVY GDFSCKEEPE IDSPRGDIGI GIQHVFTEMK

Homologie: Cow: 90%, Dog: 80%, Guinea Pig: 86%, Human: 93%, Mouse: 100%, Rabbit: 86%, Rat: 93%, Sheep: 90%

Attributs du produit: This is a rabbit polyclonal antibody against Irf1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 329 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IRF1

Antigène: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Autre désignation: Irf1 (IRF1 Produits)

Synonymes: anticorps irf1, anticorps zgc:136945, anticorps IRF1, anticorps irf11, anticorps zgc:103566, anticorps IRF-1, anticorps MAR, anticorps AU020929, anticorps Irf-1, anticorps interferon regulatory factor 1, anticorps interferon regulatory factor 1a, anticorps interferon regulatory factor 1b, anticorps IRF1, anticorps irf1a, anticorps irf1b, anticorps Irf1

Sujet: Irf1 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Irf1 acts as a tumor suppressor.
Alias Symbols: AU020929, Irf-1
Protein Interaction Partner: Ubc, Sumo1, Ube2i, Pias3, Tbk1, Polr2a,
Protein Size: 329

Poids moléculaire: 37 kDa

ID gène: 16362

NCBI Accession: NM_008390, NP_032416

UniProt: P15314

Pathways: Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy