SREBF1 anticorps (N-Term)

N° du produit ABIN2779970

Détail du produit anti-SREBF1 anticorps

Antigène: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Épitope: N-Term

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SREBF1 est non-conjugé

Application: Western Blotting (WB)

Séquence: DIEDMLQLIN NQDSDFPGLF DAPYAGGETG DTGPSSPGAN SPESFSSASL

Homologie: Mouse: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SREBF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of mouse SREBF1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1134 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SREBF1

Antigène: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Autre désignation: SREBF1 (SREBF1 Produits)

Synonymes: anticorps SREBP-1c, anticorps SREBP1, anticorps bHLHd1, anticorps ADD-1, anticorps ADD1, anticorps D630008H06, anticorps SREBP-1, anticorps SREBP-1a, anticorps SREBP1c, anticorps Srebp1, anticorps SCREBP1, anticorps SREBP-1C, anticorps SREBF1, anticorps srebp1, anticorps sterol regulatory element binding transcription factor 1, anticorps sterol regulatory element binding transcription factor 1 L homeolog, anticorps sterol regulatory element binding protein-1, anticorps Sterol regulatory element Binding Protein, anticorps SREBF1, anticorps Srebf1, anticorps srebf1.L, anticorps SREBP-1, anticorps srebf1, anticorps sbp-1

Sujet: Srebf1 is transcriptional activator that binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Srebf1 also binds to an E-box motif (5'-ATCACGTGA-3'). Srebf1 regulates the transcription of genes for sterol biosynthesis and the LDL receptor gene.
Alias Symbols: ADD1, ADD-1, SREBP1, bHLHd1, SREBP-1, SREBP1c, SREBP-1a, SREBP-1c, D630008H06
Protein Interaction Partner: Rnf20, Zbtb7c, Ppargc1b, Rela, Ewsr1, Pcbd1,
Protein Size: 1134

Poids moléculaire: 125 kDa

ID gène: 20787

NCBI Accession: NM_011480, NP_035610

UniProt: Q9WTN3

Pathways: AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha