FIGLA anticorps (C-Term)

N° du produit ABIN2779982

Cet anticorps Lapin Polyclonal détecte spécifiquement FIGLA dans WB. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour FIGLA anticorps (C-Term) (ABIN2779982)

Antigène: FIGLA (Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FIGLA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FIGLA anticorps

Épitope: C-Term

Fonction: Figla Antibody - C-terminal region

Séquence: SSTRELLGNA TQPTSCASGL KKEEEGPWAY AGHSEPLYSY HQSTVPETRS

Homologie: Mouse: 100%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against Figla. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Figla

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37173-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FIGLA

Antigène: FIGLA (Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA))

Autre désignation: Figla

Sujet:

Background Information: Figla is a germ-line specific transcription factor implicated in postnatal oocyte-specific gene expression. It plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. It is essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Figla binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.

Gene Name: folliculogenesis specific basic helix-loop-helix

Alternative Symbols: bHLHc, bHLHc8, FIGalpha

Protein Name: Factor in the germline alpha

Poids moléculaire: 21kDa

ID gène: 26910

NCBI Accession: NP_036143

UniProt: O55208